Director, Process Chemistry (South San Francisco, CA)

Sutro Biopharma, Inc. is seeking a driven and talented Director to join our Process Chemistry team as we change the future of oncology. While collaborating with cross-functional departments, you will play a key role in maximizing our technology and progressing our novel therapeutics. We are dedicated to making a difference in the lives of patients, both as individuals and as part of a team.


  • Process Chemistry representative/technical lead with Sutro project teams, Analytical Chemistry, CMC, Supply Chain, Regulatory, Quality, collaborators/clients, CROs/ CDMOs and vendors.
  • Planning of scope of work and timelines to implement access to material, incorporating starting material supply, and process development/optimization for all appropriate stages (preclinical, GLP tox, IND, Phase 2 and beyond) to facilitate access to quality material.
  • All appropriate documentation (process/optimization/campaign method reports, analytical methods (qualification and qualification), specification, purity profile, stability studies, batch records, campaign reports) for starting materials, intermediates, and target compound. Experience with Quality and Regulatory environment important.
  • Working closely with Med Chem team, enabling technical transfer of projects to CRO, covering synthetic, purification, and analytical work.


  • Experienced process chemist with expertise in the design and implementation of efficient routes to complex molecules.
  • D chemistry with post doc experience (preferred) – methodology/nature product chemist.
  • Industrial experience – Pharma/Biotech/CRO positions -CMC/process chemistry
  • Track record of management/oversight of CROs (domestic and international, e.g., China and India) contracted to take on these projects. Experience with HPAPI manufacture preferred. Experience with process validation preferred.
  • Experience in laboratory development, pilot plant scale-up and production scale technical coverage in a cGMP environment.
  • Experience with preparation and review of documentation for Regulatory submission.

Sound exciting? Apply today and join our team!

Please submit resume for Req. #2232 to Please visit our website at for more information.

Sutro provides a competitive benefits package that includes a choice of health, dental, and vision insurance, life insurance, flexible spending accounts, 401K plan, PTO, ESPP (Employee Stock Purchase Plan) and stock options.

As an equal opportunity employer, we believe in fostering a culture that is inclusive and values diversity in background and opinions. Sutro Biopharma hires extraordinary individuals into every position in the company and is committed to the diversity of our team. Our company progresses without regard of race, ethnicity, gender, sexual orientation, religious belief, age, disability or citizenship status. We are dedicated to creating a safe environment where our employees can grow and succeed together.

Salaries listed on jobsites may not be representative of salary ranges at Sutro Biopharma.

Please be advised, inquiries or resumes from recruiters will not be accepted.

Company Overview

Sutro Biopharma, Inc., located in South San Francisco, is a clinical-stage drug discovery, development and manufacturing company. Using precise protein engineering and rational design, Sutro is advancing next-generation oncology therapeutics.

Sutro is dedicated to transforming the lives of cancer patients by creating medicines with improved therapeutic profiles for areas of unmet need. To date, Sutro’s platform has led to cytokine-based immuno-oncology therapies, ADCs, vaccines and bispecific antibodies directed at precedented targets in clinical indications where the current standard of care is suboptimal.

The platform allows it to accelerate discovery and development of potential first-in-class and best-in-class molecules through rapid and systematic evaluation of protein structure-activity relationships to create optimized homogeneous product candidates.

In addition to developing its own oncology pipeline, Sutro is collaborating with select pharmaceutical and biotech companies to discover and develop novel, next-generation therapeutics. As the pace of clinical development accelerates, Sutro and its partners are developing therapeutics designed to more efficiently kill tumors without harming healthy cells.