Research Associate, Process Development Downstream (South San Francisco, CA)

The candidate hired for this position will join a productive and professional downstream process development team. You will be supporting the development of purification processes for scale up and tech transfer to GMP manufacturing. 

Lab Responsibilities:

  • Support the development, characterize, validate, and implement scalable purification process from laboratory to manufacturing scale. Designs, executes, and interprets lab results with minimal guidance.
  • Applies engineering principles, scientific knowledge, and techniques to solve problems.
  • Monitor process results, identify problems and develop solutions.
  • Conducts research and development activities with chromatography using AKTA systems, TFF UF/DF (Hollow Fiber/Cassettes), centrifugation, depth filtration, and flocculation.
  • Executes purification runs to provide support for cell-free expression studies, analytical/formulation, and Tox supply
  • Presents consolidated results to the development groups


A successful candidate is expected to have solid bench skills and good understanding of protein purification theories, methodologies, and techniques.

  • BS/MS in scientific discipline with 1- 5 years of related experience in biochemistry, chemical engineering or other relevant disciplines
  • Experience using AKTA for IEX, Affinity, HIC, MMC, and SEC
  • Ability to review and analyze experiments independently
  • Strong organization skills in experiment recording and data summary with strong attention to details.
  • Ability to communicate and work collaboratively in a team environment
  • Effective and strong problem-solving capabilities is a must.

Sound exciting? Apply today and join our team!

Please submit resume for Req. #2218 to Please visit our website at for more information.

Sutro provides a competitive benefits package that includes a choice of health, dental, and vision insurance, life insurance, flexible spending accounts, 401K plan, PTO, ESPP (Employee Stock Purchase Plan) and stock options.

As an equal opportunity employer, we believe in fostering a culture that is inclusive and values diversity in background and opinions. Sutro Biopharma hires extraordinary individuals into every position in the company and is committed to the diversity of our team. Our company progresses without regard of race, ethnicity, gender, sexual orientation, religious belief, age, disability or citizenship status. We are dedicated to creating a safe environment where our employees can grow and succeed together.

Salaries listed on jobsites may not be representative of salary ranges at Sutro Biopharma.

Please be advised, inquiries or resumes from recruiters will not be accepted.

Company Overview

Sutro Biopharma, Inc., located in South San Francisco, is a clinical-stage drug discovery, development and manufacturing company. Using precise protein engineering and rational design, Sutro is advancing next-generation oncology therapeutics.

Sutro is dedicated to transforming the lives of cancer patients by creating medicines with improved therapeutic profiles for areas of unmet need. To date, Sutro’s platform has led to cytokine-based immuno-oncology therapies, ADCs, vaccines and bispecific antibodies directed at precedented targets in clinical indications where the current standard of care is suboptimal.

The platform allows it to accelerate discovery and development of potential first-in-class and best-in-class molecules through rapid and systematic evaluation of protein structure-activity relationships to create optimized homogeneous product candidates.

In addition to developing its own oncology pipeline, Sutro is collaborating with select pharmaceutical and biotech companies to discover and develop novel, next-generation therapeutics. As the pace of clinical development accelerates, Sutro and its partners are developing therapeutics designed to more efficiently kill tumors without harming healthy cells.